Bidirectional relationships between cannabis use, anxiety and depressive symptoms in the mediation of the association with psychotic experience: further support for an affective pathway to psychosis.

Rajiv RadhakrishnanLotta-Katrin PriesGamze ErzinMargreet Ten HaveRon de GraafSaskia van DorsselaerNicole GuntherMaarten BakBart P F RuttenJim van OsSinahin Guloksuz

Published in: Psychological medicine (2022)

This first longitudinal cohort study examining the mediational relationship between cannabis use, anxiety/depressive symptoms and PE, shows that there is a bidirectional relationship between cannabis use, anxiety/depressive symptoms and PE. However, the contribution of anxiety/depressive symptoms as a mediator was greater than that of cannabis.

Keyphrases

depressive symptoms
sleep quality
social support
bipolar disorder
physical activity
cross sectional