Activation of targetable inflammatory immune signaling is seen in myelodysplastic syndromes with SF3B1 mutations.
Gaurav S ChoudharyAndrea PellagattiBogos AgianianMolly A SmithTushar D BhagatShanisha Gordon-MitchellSrabani SahuSanjay PandeyNishi ShahSrinivas AluriRitesh AggarwalSarah AminovLeya SchwartzVioletta SteeplesRobert N BooherMurali RamachandraMaria SamsonMilagros CarbajalKith PradhanTeresa V BowmanManoj M PillaiBritta WillAmittha WickremaAditi ShastriRobert K BradleyRobert E MartellUlrich G SteidlEvripidis GavathiotisJacqueline BoultwoodDaniel T StarczynowskiAmit K VermaPublished in: eLife (2022)
This work was supported by Cincinnati Children's Hospital Research Foundation, Leukemia Lymphoma Society, and National Institute of Health (R35HL135787, RO1HL111103, RO1DK102759, RO1HL114582), Gabrielle's Angel Foundation for Cancer Research, and Edward P. Evans Foundation grants to DTS. AV is supported by Edward P. Evans Foundation, National Institute of Health (R01HL150832, R01HL139487, R01CA275007), Leukemia and Lymphoma Society, Curis and a gift from the Jane and Myles P. Dempsey family. AP and JB are supported by Blood Cancer UK (grants 13042 and 19004). GC is supported by a training grant from NYSTEM. We acknowledge support of this research from The Einstein Training Program in Stem Cell Research from the Empire State Stem Cell Fund through New York State Department of Health Contract C34874GG. MS is supported by a National Institute of Health Research Training and Career Development Grant (F31HL132420).
Keyphrases
- stem cells
- healthcare
- public health
- quality improvement
- papillary thyroid
- mental health
- health information
- acute myeloid leukemia
- bone marrow
- diffuse large b cell lymphoma
- multiple sclerosis
- squamous cell
- oxidative stress
- young adults
- emergency department
- mass spectrometry
- transcription factor
- ms ms
- lymph node metastasis
- high resolution
- acute care
- protein kinase
- liquid chromatography
- simultaneous determination