Evripidis Gavathiotis

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 45

Top Venues

Nature communications

bioRxiv : the preprint server for biology

Cancer discovery

Nature

Albert Einstein College of Medicine

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Albert Einstein College of Medicine

United States

Professor :: Biochemistry / Medicine

Publications

Vanessa López-Polo, Mate Maus, Emmanouil Zacharioudakis, Miguel Lafarga, Camille Stephan-Otto Attolini, Francisco D M Marques, Marta Kovatcheva, Evripidis Gavathiotis, Manuel Serrano
Release of mitochondrial dsRNA into the cytosol is a key driver of the inflammatory phenotype of senescent cells. Nature communications 15 (1) (2024)
Stella Victorelli, Hanna Salmonowicz, James Chapman, Helene Martini, Maria Grazia Vizioli, Joel S Riley, Catherine Cloix, Ella Hall-Younger, Jair Machado Espindola-Netto, Diana Jurk, Anthony B Lagnado, Lilian Sales Gomez, Joshua N Farr, Dominik Saul, Rebecca Reed, George Kelly, Madeline Eppard, Laura C Greaves, Zhixun Dou, Nicholas Pirius, Karolina Szczepanowska, Rebecca A Porritt, Huijie Huang, Timothy Y Huang, Derek A Mann, Claudio Akio Masuda, Sundeep Khosla, Haiming Dai, Scott H Kaufmann, Emmanouil Zacharioudakis, Evripidis Gavathiotis, Nathan K LeBrasseur, Xue Lei, Alva G Sainz, Viktor I Korolchuk, Peter D Adams, Gerald S Shadel, Stephen W G Tait, João F Passos
Author Correction: Apoptotic stress causes mtDNA release during senescence and drives the SASP. Nature (2024)
Joseph Clayton, Aarion Romany, Evangelia Matenoglou, Evripidis Gavathiotis, Poulikos I Poulikakos, Jana Shen
Mechanism of Dimer Selectivity and Binding Cooperativity of BRAF Inhibitors. bioRxiv : the preprint server for biology (2024)
Joseph Clayton, Aarion Romany, Evangelia Matenoglou, Evripidis Gavathiotis, Poulikos I Poulikakos, Jana Shen
Mechanism of Dimer Selectivity and Binding Cooperativity of BRAF Inhibitors. bioRxiv : the preprint server for biology (2024)
Joseph Clayton, Aarion Romany, Evangelia Matenoglou, Evripidis Gavathiotis, Poulikos I Poulikakos, Jana Shen
Mechanism of Dimer Selectivity and Binding Cooperativity of BRAF Inhibitors. bioRxiv : the preprint server for biology (2024)
Joseph Clayton, Aarion Romany, Evangelia Matenoglou, Evripidis Gavathiotis, Poulikos I Poulikakos, Jana Shen
Mechanism of Dimer Selectivity and Binding Cooperativity of BRAF Inhibitors. bioRxiv : the preprint server for biology (2024)
Joseph Clayton, Aarion Romany, Evangelia Matenoglou, Evripidis Gavathiotis, Poulikos I Poulikakos, Jana Shen
Mechanism of Dimer Selectivity and Binding Cooperativity of BRAF Inhibitors. bioRxiv : the preprint server for biology (2024)
Cara A Reynolds, Sandra Pelka, Floralba Gjergjova, Inmaculada Tasset, Rabia R Khawaja, Kristen L Lindenau, Gregory J Krause, Evripidis Gavathiotis, Ana Maria Cuervo, Fernando Macian
Restoration of LAMP2A expression in old mice leads to changes in the T cell compartment that support improved immune function. Proceedings of the National Academy of Sciences of the United States of America 121 (38) (2024)
Vanessa López-Polo, Mate Maus, Emmanouil Zacharioudakis, Miguel Lafarga, Camille Stephan-Otto Attolini, Francisco D M Marques, Marta Kovatcheva, Evripidis Gavathiotis, Manuel Serrano
Release of mitochondrial dsRNA into the cytosol is a key driver of the inflammatory phenotype of senescent cells. Nature communications 15 (1) (2024)
Nadege Gitego, Bogos Agianian, Oi Wei Mak, Vasantha Kumar Mv, Emily H Cheng, Evripidis Gavathiotis
Chemical modulation of cytosolic BAX homodimer potentiates BAX activation and apoptosis. Nature communications 14 (1) (2023)
Joseph Clayton, Aarion Romany, Evangelia Matenoglou, Evripidis Gavathiotis, Poulikos I Poulikakos, Jana Shen
Mechanism of Dimer Selectivity and Binding Cooperativity of BRAF inhibitors. bioRxiv : the preprint server for biology (2023)
Nadege Gitego, Bogos Agianian, Oi Wei Mak, Vasantha Kumar Mv, Emily H Cheng, Evripidis Gavathiotis
Chemical modulation of cytosolic BAX homodimer potentiates BAX activation and apoptosis. Nature communications 14 (1) (2023)
Christina Glytsou, Xufeng Chen, Emmanouil Zacharioudakis, Wafa Al-Santli, Hua Zhou, Bettina Nadorp, Soobeom Lee, Audrey Lasry, Zhengxi Sun, Dimitrios Papaioannou, Michael Cammer, Kun Wang, Tomasz Zal, Malgorzata Anna Zal, Bing Z Carter, Jo Ishizawa, Raoul Tibes, Aristotelis Tsirigos, Michael Andreeff, Evripidis Gavathiotis, Iannis Aifantis
Mitophagy promotes resistance to BH3 mimetics in acute myeloid leukemia. Cancer discovery (2023)
Stella Victorelli, Hanna Salmonowicz, James Chapman, Helene Martini, Maria Grazia Vizioli, Joel S Riley, Catherine Cloix, Ella Hall-Younger, Jair Machado Espindola-Netto, Diana Jurk, Anthony B Lagnado, Lilian Sales Gomez, Joshua N Farr, Dominik Saul, Rebecca Reed, George Kelly, Madeline Eppard, Laura C Greaves, Zhixun Dou, Nicholas Pirius, Karolina Szczepanowska, Rebecca A Porritt, Huijie Huang, Timothy Y Huang, Derek A Mann, Claudio Akio Masuda, Sundeep Khosla, Haiming Dai, Scott H Kaufmann, Emmanouil Zacharioudakis, Evripidis Gavathiotis, Nathan K LeBrasseur, Xue Lei, Alva G Sainz, Viktor I Korolchuk, Peter D Adams, Gerald S Shadel, Stephen W G Tait, João F Passos
Apoptotic stress causes mtDNA release during senescence and drives the SASP. Nature (2023)
Joseph Clayton, Aarion Romany, Evangelia Matenoglou, Evripidis Gavathiotis, Poulikos I Poulikakos, Jana Shen
Mechanism of Dimer Selectivity and Binding Cooperativity of BRAF inhibitors. bioRxiv : the preprint server for biology (2023)
Christina Glytsou, Xufeng Chen, Emmanouil Zacharioudakis, Wafa Al-Santli, Hua Zhou, Bettina Nadorp, Soobeom Lee, Audrey Lasry, Zhengxi Sun, Dimitrios Papaioannou, Michael Cammer, Kun Wang, Tomasz Zal, Malgorzata Anna Zal, Bing Z Carter, Jo Ishizawa, Raoul Tibes, Aristotelis Tsirigos, Michael Andreeff, Evripidis Gavathiotis, Iannis Aifantis
Mitophagy promotes resistance to BH3 mimetics in acute myeloid leukemia. Cancer discovery (2023)
Christina Glytsou, Xufeng Chen, Emmanouil Zacharioudakis, Wafa Al-Santli, Hua Zhou, Bettina Nadorp, Soobeom Lee, Audrey Lasry, Zhengxi Sun, Dimitrios Papaioannou, Michael Cammer, Kun Wang, Tomasz Zal, Malgorzata Anna Zal, Bing Z Carter, Jo Ishizawa, Raoul Tibes, Aristotelis Tsirigos, Michael Andreeff, Evripidis Gavathiotis, Iannis Aifantis
Mitophagy promotes resistance to BH3 mimetics in acute myeloid leukemia. Cancer discovery (2023)
Nadege Gitego, Bogos Agianian, Oi Wei Mak, Vasantha Kumar Mv, Emily H Cheng, Evripidis Gavathiotis
Chemical modulation of cytosolic BAX homodimer potentiates BAX activation and apoptosis. Nature communications 14 (1) (2023)
Christina Glytsou, Xufeng Chen, Emmanouil Zacharioudakis, Wafa Al-Santli, Hua Zhou, Bettina Nadorp, Soobeom Lee, Audrey Lasry, Zhengxi Sun, Dimitrios Papaioannou, Michael Cammer, Kun Wang, Tomasz Zal, Malgorzata Anna Zal, Bing Z Carter, Jo Ishizawa, Raoul Tibes, Aristotelis Tsirigos, Michael Andreeff, Evripidis Gavathiotis, Iannis Aifantis
Mitophagy promotes resistance to BH3 mimetics in acute myeloid leukemia. Cancer discovery (2023)
Christina Glytsou, Xufeng Chen, Emmanouil Zacharioudakis, Wafa Al-Santli, Hua Zhou, Bettina Nadorp, Soobeom Lee, Audrey Lasry, Zhengxi Sun, Dimitrios Papaioannou, Michael Cammer, Kun Wang, Tomasz Zal, Malgorzata Anna Zal, Bing Z Carter, Jo Ishizawa, Raoul Tibes, Aristotelis Tsirigos, Michael Andreeff, Evripidis Gavathiotis, Iannis Aifantis
Mitophagy promotes resistance to BH3 mimetics in acute myeloid leukemia. Cancer discovery (2023)
Christina Glytsou, Xufeng Chen, Emmanouil Zacharioudakis, Wafa Al-Santli, Hua Zhou, Bettina Nadorp, Soobeom Lee, Audrey Lasry, Zhengxi Sun, Dimitrios Papaioannou, Michael Cammer, Kun Wang, Tomasz Zal, Malgorzata Anna Zal, Bing Z Carter, Jo Ishizawa, Raoul Tibes, Aristotelis Tsirigos, Michael Andreeff, Evripidis Gavathiotis, Iannis Aifantis
Mitophagy promotes resistance to BH3 mimetics in acute myeloid leukemia. Cancer discovery (2023)
Aslamuzzaman Kazi, Alok Ranjan, Vasantha Kumar M V, Bogos Agianian, Martin Garcia Chavez, Vignesh Vudatha, Rui Wang, Rajanikanth Vangipurapu, Liwei Chen, Perry Kennedy, Karthikeyan Subramanian, Jonathan C K Quirke, Francisca Beato, Patrick W Underwood, Jason B Fleming, Jose G Trevino, Paul J Hergenrother, Evripidis Gavathiotis, Said M Sebti
Discovery of KRB-456, a KRAS G12D switch-I/II allosteric pocket binder that inhibits the growth of pancreatic cancer patient-derived tumors. Cancer research communications (2023)
Joseph Clayton, Aarion Romany, Evangelia Matenoglou, Evripidis Gavathiotis, Poulikos I Poulikakos, Jana Shen
Mechanism of Dimer Selectivity and Binding Cooperativity of BRAF inhibitors. bioRxiv : the preprint server for biology (2023)
Nadege Gitego, Bogos Agianian, Oi Wei Mak, Vasantha Kumar Mv, Emily H Cheng, Evripidis Gavathiotis
Chemical modulation of cytosolic BAX homodimer potentiates BAX activation and apoptosis. Nature communications 14 (1) (2023)
Christina Glytsou, Xufeng Chen, Emmanouil Zacharioudakis, Wafa Al-Santli, Hua Zhou, Bettina Nadorp, Soobeom Lee, Audrey Lasry, Zhengxi Sun, Dimitrios Papaioannou, Michael Cammer, Kun Wang, Tomasz Zal, Malgorzata Anna Zal, Bing Z Carter, Jo Ishizawa, Raoul Tibes, Aristotelis Tsirigos, Michael Andreeff, Evripidis Gavathiotis, Iannis Aifantis
Mitophagy promotes resistance to BH3 mimetics in acute myeloid leukemia. Cancer discovery (2023)
Joseph Clayton, Aarion Romany, Evangelia Matenoglou, Evripidis Gavathiotis, Poulikos I Poulikakos, Jana Shen
Mechanism of Dimer Selectivity and Binding Cooperativity of BRAF inhibitors. bioRxiv : the preprint server for biology (2023)
Nadege Gitego, Bogos Agianian, Oi Wei Mak, Vasantha Kumar Mv, Emily H Cheng, Evripidis Gavathiotis
Chemical modulation of cytosolic BAX homodimer potentiates BAX activation and apoptosis. Nature communications 14 (1) (2023)
Joseph Clayton, Aarion Romany, Evangelia Matenoglou, Evripidis Gavathiotis, Poulikos I Poulikakos, Jana Shen
Mechanism of Dimer Selectivity and Binding Cooperativity of BRAF inhibitors. bioRxiv : the preprint server for biology (2023)
Susmita Kaushik, Yves R Juste, Kristen L Lindenau, Shuxian Dong, Adrián Macho-González, Olaya Santiago-Fernández, Mericka McCabe, Rajat Singh, Evripidis Gavathiotis, Ana Maria Cuervo
Chaperone-mediated autophagy regulates adipocyte differentiation. Science advances 8 (46) (2022)
Andrea Lopez, Denis E Reyna, Nadege Gitego, Felix Kopp, Hua Zhou, Miguel A Miranda-Roman, Lars Ulrik Nordstrøm, Swathi-Rao Narayanagari, Ping Chi, Eduardo Vilar, Aristotelis Tsirigos, Evripidis Gavathiotis
Co-targeting of BAX and BCL-XL proteins broadly overcomes resistance to apoptosis in cancer. Nature communications 13 (1) (2022)
Gaurav S Choudhary, Andrea Pellagatti, Bogos Agianian, Molly A Smith, Tushar D Bhagat, Shanisha Gordon-Mitchell, Srabani Sahu, Sanjay Pandey, Nishi Shah, Srinivas Aluri, Ritesh Aggarwal, Sarah Aminov, Leya Schwartz, Violetta Steeples, Robert N Booher, Murali Ramachandra, Maria Samson, Milagros Carbajal, Kith Pradhan, Teresa V Bowman, Manoj M Pillai, Britta Will, Amittha Wickrema, Aditi Shastri, Robert K Bradley, Robert E Martell, Ulrich G Steidl, Evripidis Gavathiotis, Jacqueline Boultwood, Daniel T Starczynowski, Amit K Verma
Activation of targetable inflammatory immune signaling is seen in myelodysplastic syndromes with SF3B1 mutations. eLife 11 (2022)
Emmanouil Zacharioudakis, Bogos Agianian, Vasantha Kumar Mv, Nikolaos Biris, Thomas P Garner, Inna Rabinovich-Nikitin, Amanda T Ouchida, Victoria Margulets, Lars Ulrik Nordstrøm, Joel S Riley, Igor Dolgalev, Yun Chen, Andre J H Wittig, Ryan Pekson, Chris Mathew, Peter Wei, Aristotelis Tsirigos, Stephen W G Tait, Lorrie A Kirshenbaum, Richard N Kitsis, Evripidis Gavathiotis
Modulating mitofusins to control mitochondrial function and signaling. Nature communications 13 (1) (2022)
Raquel Gomez-Sintes, Qisheng Xin, Juan Ignacio Jiménez-Loygorri, Mericka McCabe, Antonio Diaz, Thomas P Garner, Xiomaris M Cotto-Rios, Yang Wu, Shuxian Dong, Cara A Reynolds, Bindi Patel, Pedro de la Villa, Fernando Macian, Patricia Boya, Evripidis Gavathiotis, Ana Maria Cuervo
Targeting retinoic acid receptor alpha-corepressor interaction activates chaperone-mediated autophagy and protects against retinal degeneration. Nature communications 13 (1) (2022)
Nora E Rahmani, Nandini Ramachandra, Srabani Sahu, Nadege Gitego, Andrea Lopez, Kith Pradhan, Tushar D Bhagat, Shanisha Gordon-Mitchell, Bianca Rivera Pena, Mohammad Kazemi, Keshav Rao, Orsi Giricz, Shahina Bano Maqbool, Raul Olea, Yongmei Zhao, Jinghang Zhang, Hamid Dolatshad, Vickram Tittrea, Dharamveer Tatwavedi, Shalini Singh, Juseong Lee, Tianyu Sun, Ulrich Steidl, Aditi Shastri, Daichi Inoue, Omar Abdel-Wahab, Andrea Pellagatti, Evripidis Gavathiotis, Jacqueline Boultwood, Amit K Verma
ASXL1 mutations are associated with distinct epigenomic alterations that lead to sensitivity to venetoclax and azacytidine. Blood cancer journal 11 (9) (2021)
Nicholas J Gadsden, Cory D Fulcher, Daniel Li, Nitisha Shrivastava, Carlos Thomas, Jeffrey E Segall, Michael B Prystowsky, Nicolas F Schlecht, Evripidis Gavathiotis, Thomas J Ow
Palbociclib Renders Human Papilloma Virus-Negative Head and Neck Squamous Cell Carcinoma Vulnerable to the Senolytic Agent Navitoclax. Molecular cancer research : MCR 19 (5) (2021)
Shuxian Dong, Qian Wang, Yun-Ruei Kao, Antonio Diaz, Inmaculada Tasset, Susmita Kaushik, Victor Thiruthuvanathan, Aliona Zintiridou, Edward Nieves, Monika Dzieciatkowska, Julie A Reisz, Evripidis Gavathiotis, Angelo D'Alessandro, Britta Will, Ana Maria Cuervo
Chaperone-mediated autophagy sustains haematopoietic stem-cell function. Nature 591 (7848) (2021)
Mathieu Bourdenx, Evripidis Gavathiotis, Ana Maria Cuervo
Chaperone-mediated autophagy: a gatekeeper of neuronal proteostasis. Autophagy 17 (8) (2021)
Adam Z Spitz, Emmanouil Zacharioudakis, Denis E Reyna, Thomas P Garner, Evripidis Gavathiotis
Eltrombopag directly inhibits BAX and prevents cell death. Nature communications 12 (1) (2021)
Dulguun Amgalan, Thomas P Garner, Ryan Pekson, Xiaotong F Jia, Mounica Yanamandala, Victor Paulino, Felix G Liang, J Jose Corbalan, Jaehoon Lee, Yun Chen, George S Karagiannis, Luis Rivera Sanchez, Huizhi Liang, Swathi-Rao Narayanagari, Kelly Mitchell, Andrea Lopez, Victoria Margulets, Marco Scarlata, Joseph H Taube, Aarti Asnani, Randall T Peterson, Rachel B Hazan, John S Condeelis, Maja H Oktay, Ulrich Steidl, Lorrie A Kirshenbaum, Evripidis Gavathiotis, Richard N Kitsis
A small-molecule allosteric inhibitor of BAX protects against doxorubicin-induced cardiomyopathy. Nature cancer 1 (3) (2020)
Xiomaris M Cotto-Rios, Bogos Agianian, Nadege Gitego, Emmanouil Zacharioudakis, Orsi Giricz, Yang Wu, Yiyu Zou, Amit Verma, Poulikos I Poulikakos, Evripidis Gavathiotis
Inhibitors of BRAF dimers using an allosteric site. Nature communications 11 (1) (2020)
Xufeng Chen, Christina Glytsou, Hua Zhou, Sonali Narang, Denis E Reyna, Andrea Lopez, Theodore Sakellaropoulos, Yixiao Gong, Andreas Kloetgen, Yoon Sing Yap, Eric Wang, Evripidis Gavathiotis, Aristotelis Tsirigos, Raoul Tibes, Iannis Aifantis
Targeting Mitochondrial Structure Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment. Cancer discovery 9 (7) (2019)
Thomas P Garner, Dulguun Amgalan, Denis E Reyna, Sheng Li, Richard N Kitsis, Evripidis Gavathiotis
Small-molecule allosteric inhibitors of BAX. Nature chemical biology 15 (4) (2019)
Bogos Agianian, Evripidis Gavathiotis
Current Insights of BRAF Inhibitors in Cancer. Journal of medicinal chemistry 61 (14) (2018)
Qi Zhang, Jingyu Zhang, Evripidis Gavathiotis
ICBS 2017 in Shanghai-Illuminating Life with Chemical Innovation. ACS chemical biology 13 (5) (2018)
Agostinho G Rocha, Antonietta Franco, Andrzej M Krezel, Jeanne M Rumsey, Justin M Alberti, William C Knight, Nikolaos Biris, Emmanouil Zacharioudakis, James W Janetka, Robert H Baloh, Richard N Kitsis, Daria-Mochly Rosen, R Reid Townsend, Evripidis Gavathiotis, Gerald W Dorn
MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A. Science (New York, N.Y.) 360 (6386) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Evripidis Gavathiotis