Robert K Bradley (Robert Bradley)

ORCID

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 41

Top Venues

eLife

Nature communications

Nature reviews. Cancer

Life science alliance

Fred Hutchinson Cancer Research Center

University of California Berkeley (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Fred Hutchinson Cancer Research Center

United States

Full Professor

Massachusetts Institute of Technology

United States

Postdoctoral Fellow :: Biology

University of California Berkeley

United States

Postdoctoral Associate :: Molecular & Cellular Biology, Mathematics

KEK | High Energy Accelerator Research Organization

Japan

Visitor :: Theory Center

Education History

University of California Berkeley

United States

PHD :: Biophysics

Publications

Martina Sarchi, Courtnee A Clough, Edie I Crosse, Jason Kim, Laura D Baquero Galvis, Nelli Aydinyan, Rachel Wellington, Feini Yang, Anna Galli, J Philip Creamer, Sintra Stewart, Robert K Bradley, Luca Malcovati, Sergei Doulatov
Mis-splicing of mitotic regulators sensitizes SF3B1-mutated human HSCs to CHK1 inhibition. Blood cancer discovery (2024)
Austin M Gabel, Andrea E Belleville, James D Thomas, Siegen A McKellar, Taylor R Nicholas, Toshihiro Banjo, Edie I Crosse, Robert K Bradley
Multiplexed screening reveals how cancer-specific alternative polyadenylation shapes tumor growth in vivo. Nature communications 15 (1) (2024)
Andrea E Belleville, James D Thomas, Jackson Tonnies, Austin M Gabel, Andrea Borrero Rossi, Priti Singh, Christine Queitsch, Robert K Bradley
An autoregulatory poison exon in Smndc1 is conserved across kingdoms and influences organism growth. PLoS genetics 20 (8) (2024)
Andrea E Belleville, James D Thomas, Jackson Tonnies, Austin M Gabel, Andrea Borrero Rossi, Priti Singh, Christine Queitsch, Robert K Bradley
An autoregulatory poison exon in Smndc1 is conserved across kingdoms and influences organism growth. PLoS genetics 20 (8) (2024)
Andrea E Belleville, James D Thomas, Jackson Tonnies, Austin M Gabel, Andrea Borrero Rossi, Priti Singh, Christine Queitsch, Robert K Bradley
An autoregulatory poison exon in Smndc1 is conserved across kingdoms and influences organism growth. PLoS genetics 20 (8) (2024)
Jose Mario Bello Pineda, Robert K Bradley
DUX4 is a common driver of immune evasion and immunotherapy failure in metastatic cancers. eLife 12 (2024)
Jose Mario Bello Pineda, Robert K Bradley
DUX4 is a common driver of immune evasion and immunotherapy failure in metastatic cancers. eLife 12 (2024)
Austin M Gabel, Andrea E Belleville, James D Thomas, Siegen A McKellar, Taylor R Nicholas, Toshihiro Banjo, Edie I Crosse, Robert K Bradley
Multiplexed screening reveals how cancer-specific alternative polyadenylation shapes tumor growth in vivo. Nature communications 15 (1) (2024)
Jose Mario Bello Pineda, Robert K Bradley
DUX4 is a common driver of immune evasion and immunotherapy failure in metastatic cancers. eLife 12 (2024)
Austin M Gabel, Andrea E Belleville, James D Thomas, Siegen A McKellar, Taylor R Nicholas, Toshihiro Banjo, Edie I Crosse, Robert K Bradley
Multiplexed screening reveals how cancer-specific alternative polyadenylation shapes tumor growth in vivo. Nature communications 15 (1) (2024)
Jose Mario Bello Pineda, Robert K Bradley
DUX4 is a common driver of immune evasion and immunotherapy failure in metastatic cancers. eLife 12 (2024)
Austin M Gabel, Andrea E Belleville, James D Thomas, Siegen A McKellar, Taylor R Nicholas, Toshihiro Banjo, Edie I Crosse, Robert K Bradley
Multiplexed screening reveals how cancer-specific alternative polyadenylation shapes tumor growth in vivo. Nature communications 15 (1) (2024)
Jose Mario Bello Pineda, Robert K Bradley
DUX4 is a common driver of immune evasion and immunotherapy failure in metastatic cancers. eLife 12 (2024)
Martina Sarchi, Courtnee A Clough, Edie I Crosse, Jason Kim, Laura D Baquero Galvis, Nelli Aydinyan, Rachel Wellington, Feini Yang, Anna Galli, J Philip Creamer, Sintra Stewart, Robert K Bradley, Luca Malcovati, Sergei Doulatov
Mis-splicing of Mitotic Regulators Sensitizes SF3B1-Mutated Human HSCs to CHK1 Inhibition. Blood cancer discovery 5 (5) (2024)
Jose Mario Bello Pineda, Robert K Bradley
DUX4 is a common driver of immune evasion and immunotherapy failure in metastatic cancers. eLife 12 (2024)
Robert K Bradley, Olga Anczukow
RNA splicing dysregulation and the hallmarks of cancer. Nature reviews. Cancer (2023)
Jose Mario Bello Pineda, Robert K Bradley
DUX4 is a common driver of immune evasion and immunotherapy failure in metastatic cancers. bioRxiv : the preprint server for biology (2023)
Emma R Hoppe, Dylan B Udy, Robert K Bradley
Recursive splicing discovery using lariats in total RNA sequencing. Life science alliance 6 (7) (2023)
Robert K Bradley, Olga Anczukow
RNA splicing dysregulation and the hallmarks of cancer. Nature reviews. Cancer 23 (3) (2023)
Emma R Hoppe, Dylan B Udy, Robert K Bradley
Recursive splicing discovery using lariats in total RNA sequencing. Life science alliance 6 (7) (2023)
Emma R Hoppe, Dylan B Udy, Robert K Bradley
Recursive splicing discovery using lariats in total RNA sequencing. Life science alliance 6 (7) (2023)
Robert K Bradley, Olga Anczukow
RNA splicing dysregulation and the hallmarks of cancer. Nature reviews. Cancer 23 (3) (2023)
Emma R Hoppe, Dylan B Udy, Robert K Bradley
Recursive splicing discovery using lariats in total RNA sequencing. Life science alliance 6 (7) (2023)
Robert K Bradley, Olga Anczukow
RNA splicing dysregulation and the hallmarks of cancer. Nature reviews. Cancer 23 (3) (2023)
Pinpin Sui, Guo Ge, Shi Chen, Jiaojiao Bai, Ivan P Rubalcava, Hui Yang, Ying Guo, Peng Zhang, Ying Li, Edward A Medina, Mingjiang Xu, Omar Abdel-Wahab, Robert K Bradley, Feng-Chun Yang
SRSF2 mutation cooperates with ASXL1 truncated alteration to accelerate leukemogenesis. Leukemia (2023)
Robert K Bradley, Olga Anczukow
RNA splicing dysregulation and the hallmarks of cancer. Nature reviews. Cancer 23 (3) (2023)
Khrystyna North, Salima Benbarche, Bo Liu, Joseph Pangallo, Sisi Chen, Maximilian Stahl, Jan Philipp Bewersdorf, Robert F Stanley, Caroline Erickson, Hana Cho, Jose Mario Bello Pineda, James D Thomas, Jacob T Polaski, Andrea E Belleville, Austin M Gabel, Dylan B Udy, Olivier Humbert, Hans-Peter Kiem, Omar Abdel-Wahab, Robert K Bradley
Synthetic introns enable splicing factor mutation-dependent targeting of cancer cells. Nature biotechnology 40 (7) (2022)
Gaurav S Choudhary, Andrea Pellagatti, Bogos Agianian, Molly A Smith, Tushar D Bhagat, Shanisha Gordon-Mitchell, Srabani Sahu, Sanjay Pandey, Nishi Shah, Srinivas Aluri, Ritesh Aggarwal, Sarah Aminov, Leya Schwartz, Violetta Steeples, Robert N Booher, Murali Ramachandra, Maria Samson, Milagros Carbajal, Kith Pradhan, Teresa V Bowman, Manoj M Pillai, Britta Will, Amittha Wickrema, Aditi Shastri, Robert K Bradley, Robert E Martell, Ulrich G Steidl, Evripidis Gavathiotis, Jacqueline Boultwood, Daniel T Starczynowski, Amit K Verma
Activation of targetable inflammatory immune signaling is seen in myelodysplastic syndromes with SF3B1 mutations. eLife 11 (2022)
Dylan B Udy, Robert K Bradley
Nonsense-mediated mRNA decay uses complementary mechanisms to suppress mRNA and protein accumulation. Life science alliance 5 (3) (2021)
Athea Vichas, Amanda K Riley, Naomi T Nkinsi, Shriya Kamlapurkar, Pheobe C R Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew G Rees, Austin M Gabel, James D Thomas, Robert K Bradley, John K Lee, Emily M Hatch, Marina K Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H Berger
Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer. Nature communications 12 (1) (2021)
Courtnee A Clough, Joseph Pangallo, Martina Sarchi, Janine O Ilagan, Khrystyna North, Rochelle Bergantinos, Massiel Chavez Stolla, Jasmine Naru, Patrick J Nugent, Eunhee Kim, Derek L Stirewalt, Arvind Rasi Subramaniam, Omar Abdel-Wahab, Janis L Abkowitz, Robert K Bradley, Sergei Doulatov
Coordinated mis-splicing of TMEM14C and ABCB7 causes ring sideroblast formation in SF3B1-mutant myelodysplastic syndrome. Blood (2021)
Daichi Inoue, Jacob T Polaski, Justin Taylor, Hatice Ulku Osmanbeyoglu, Sisi Chen, Susumu Kobayashi, Simon J Hogg, Yasutaka Hayashi, Jose Mario Bello Pineda, Ettaib El Marabti, Caroline Erickson, Katherine Knorr, Miki Fukumoto, Hiromi Yamazaki, Atsushi Tanaka, Chie Fukui, Sydney X Lu, Benjamin H Durham, Bo Liu, Eric Wang, Sanjoy Mehta, Daniel Zakheim, Ralph Garippa, Alex Penson, Guo-Liang Chew, Frank McCormick, Robert K Bradley, Omar Abdel-Wahab
Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition. Nature genetics 53 (5) (2021)
Jacob T Polaski, Dylan B Udy, Luisa F Escobar-Hoyos, Gokce Askan, Steven D Leach, Andrea Ventura, Ram Kannan, Robert K Bradley
The origins and consequences of UPF1 variants in pancreatic adenosquamous carcinoma. eLife 10 (2021)
Sumiko Takao, Lauren Forbes, Masahiro Uni, Shuyuan Cheng, Jose Mario Bello Pineda, Yusuke Tarumoto, Paolo Cifani, Gerard Minuesa, Celine Chen, Michael G Kharas, Robert K Bradley, Christopher R Vakoc, Richard P Koche, Alex Kentsis
Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia. eLife 10 (2021)
Guo-Liang Chew, Marie Bleakley, Robert K Bradley, Harmit S Malik, Steven Henikoff, Antoine Molaro, Jay F Sarthy
Short H2A histone variants are expressed in cancer. Nature communications 12 (1) (2021)
Shamin Li, Yannick Simoni, Summer Zhuang, Austin M Gabel, Shaokang Ma, Jonathan Chee, Laura V Islas, Anthony Cessna, Jenette Creaney, Robert K Bradley, Alec James Redwood, Bruce W S Robinson, Evan William Newell
Characterization of neoantigen-specific T cells in cancer resistant to immune checkpoint therapies. Proceedings of the National Academy of Sciences of the United States of America 118 (30) (2021)
James D Thomas, Jacob T Polaski, Qing Feng, Emma J De Neef, Emma R Hoppe, Maria V McSharry, Joseph Pangallo, Austin M Gabel, Andrea E Belleville, Jacqueline Watson, Naomi T Nkinsi, Alice H Berger, Robert K Bradley
RNA isoform screens uncover the essentiality and tumor-suppressor activity of ultraconserved poison exons. Nature genetics 52 (1) (2020)
Sujatha Jagannathan, Yuko Ogata, Philip R Gafken, Stephen J Tapscott, Robert K Bradley
Quantitative proteomics reveals key roles for post-transcriptional gene regulation in the molecular pathology of facioscapulohumeral muscular dystrophy. eLife 8 (2019)
Dennis Liang Fei, Tao Zhen, Benjamin Durham, John Ferrarone, Tuo Zhang, Lisa Garrett, Akihide Yoshimi, Omar Abdel-Wahab, Robert K Bradley, Paul Liu, Harold Varmus
Impaired hematopoiesis and leukemia development in mice with a conditional knock-in allele of a mutant splicing factor gene U2af1. Proceedings of the National Academy of Sciences of the United States of America 115 (44) (2018)
Dennis Liang Fei, Hayley Motowski, Rakesh Chatrikhi, Sameer Prasad, Jovian Yu, Shaojian Gao, Clara L Kielkopf, Robert K Bradley, Harold Varmus
Wild-Type U2AF1 Antagonizes the Splicing Program Characteristic of U2AF1-Mutant Tumors and Is Required for Cell Survival. PLoS genetics 12 (10) (2016)
Stanley Chun-Wei Lee, Heidi Dvinge, Eunhee Kim, Hana Cho, Jean-Baptiste Micol, Young Rock Chung, Benjamin H Durham, Akihide Yoshimi, Young Joon Kim, Michael Thomas, Camille Lobry, Chun-Wei Chen, Alessandro Pastore, Justin Taylor, Xujun Wang, Andrei Krivtsov, Scott A Armstrong, James Palacino, Silvia Buonamici, Peter G Smith, Robert K Bradley, Omar Abdel-Wahab
Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins. Nature medicine 22 (6) (2016)
Heidi Dvinge, Rhonda E Ries, Janine O Ilagan, Derek L Stirewalt, Soheil Meshinchi, Robert K Bradley
Sample processing obscures cancer-specific alterations in leukemic transcriptomes. Proceedings of the National Academy of Sciences of the United States of America 111 (47) (2014)

Robert K Bradley.css-eqlu8i{font-size:small;padding-left:4px;} (Robert Bradley)

Publication Activity (10 Years)

Top Topics

Top Venues

Robert K Bradley (Robert Bradley)