Structure-Specific Fermentation of Galacto-Oligosaccharides, Isomalto-Oligosaccharides and Isomalto/Malto-Polysaccharides by Infant Fecal Microbiota and Impact on Dendritic Cell Cytokine Responses.
Madelon J LogtenbergRenate AkkermanRosan G HobéKristel M H DonnersSander S Van LeeuwenGerben D A HermesBart J de HaanMarijke M FaasPiet L BuwaldaErwin G ZoetendalPaul de VosHenk Arie ScholsPublished in: Molecular nutrition & food research (2021)
The IMO preparation, containing reducing and non-reducing isomers, shows similar fermentation patterns as GOS in fecal microbiota of 2-week-old infants. Knowledge obtained on the substrate specificities of infant fecal microbiota and the subsequent regulatory effects of GOS, IMO and IMMP on DC responses might contribute to the design of tailored NDC mixtures for infants of different age groups.