Reduced menin expression leads to decreased ERα expression and is correlated with the occurrence of human luminal B-like and ER-negative breast cancer subtypes.
Romain TeinturierRazan Abou ZikiLoay KassemYakun LuoLucie MalbeteauSamuele GherardiLaura CorboPhilippe BertolinoThomas BachelotIsabelle TreilleuxChang Xian ZhangMuriel Le RomancerPublished in: Breast cancer research and treatment (2021)
Taken together, our data provide clues to the important role of menin in ERα regulation and the formation of breast cancer subtypes.