Impact of renal function on the prognosis of patients receiving Atezolizumab / Bevacizumab combination therapy and Lenvatinib monotherapy for unresectable hepatocellular carcinoma.
Hitomi TakadaKoji YamashitaLeona OsawaYasuyuki KomiyamaNatsuko NakakukiMasaru MuraokaYuichiro SuzukiMitsuaki SatoShinichi TakanoMitsuharu FukasawaTatsuya YamaguchiShinya MaekawaKazuya TakahashiKohei UchimuraNobuyuki EnomotoPublished in: Oncology (2023)
In patients receiving AB and LEN therapy, baseline proteinuria was associated with OS. Renal function deterioration without proteinuria was associated with a poor prognosis in AB therapy. Excessive salt intake, pre-existing atherosclerotic disease, and drug with a high risk of renal dysfunction were risk factors for renal deterioration.