PARK7 deficiency inhibits fatty acid β-oxidation via PTEN to delay liver regeneration after hepatectomy.

Xiaoye Qu Yankai WenJunzhe JiaoJie ZhaoXuehua SunFang WangYueqiu GaoWeifeng TanQiang XiaHailong WuXiaoni Kong

Published in: Clinical and translational medicine (2022)

mice CONCLUSION: Park7/Dj1 is a novel regulator of PTEN-dependent fatty acid β-oxidation, and increasing Park7 expression might be a promising strategy to promote liver regeneration.

Keyphrases

fatty acid
stem cells
cell proliferation
pi k akt
hydrogen peroxide
poor prognosis
transcription factor
wound healing
type diabetes
signaling pathway
electron transfer
nitric oxide
long non coding rna
skeletal muscle
binding protein
visible light