Functional Impact of the FADS1 rs174546 Single Nucleotide Polymorphism on Serum Lipid Levels: Insights from Molecular Mechanisms and Therapeutic Perspectives in Korean Population.
Kyun-Hee LeeSoon-Hee KimSunmin ParkHyun-Jun JangMin Jung KimHye Jeong YangHaeng Jeon HurJin Hee KimMyung Sunny KimPublished in: Molecular nutrition & food research (2024)
FADS1_rs174546T is a crucial risk factor for hypertriglyceridemia in the Koreans potentially through the interaction with miR-6728-3p. Formononetin can be a potent dietary intervention to prevent and improve hypertriglyceridemia in both rs174546 (C/T) populations.