Serious infections in ANCA-associated vasculitides in the biologic era: real-life data from a multicenter cohort of 162 patients.
Konstantinos ThomasEvangelia ArgyriouNoemin KapsalaAlexandros PanagiotopoulosAglaia ChalkiaEmilia HadziyannisKyriaki BokiPelagia KatsimbriDimitrios T BoumpasPanagiota GiannouDimitrios PetrasDimitrios VassilopoulosPublished in: Arthritis research & therapy (2021)
In this real-life study of patients with AAV, the SI incidence was higher during CYC compared to RTX induction while there was no difference between RTX and other agents used for maintenance therapy. Higher disease activity at baseline and need for PLEX and/or dialysis were independent factors associated with an SI.
Keyphrases
- disease activity
- end stage renal disease
- rheumatoid arthritis
- chronic kidney disease
- systemic lupus erythematosus
- peritoneal dialysis
- rheumatoid arthritis patients
- ankylosing spondylitis
- ejection fraction
- newly diagnosed
- prognostic factors
- electronic health record
- juvenile idiopathic arthritis
- clinical trial
- cross sectional
- bone marrow
- patient reported outcomes
- artificial intelligence
- replacement therapy