Integrated, Longitudinal Analysis of Cell-free DNA in Uveal Melanoma.
Derek WongPing LuoNadia ZnassiDiana Paola Arteaga CeballosDiana GrayArnavaz DaneshMing HanEric Y ZhaoStephanie PedersenStephenie D ProkopecYogi SundaravadanamDax TortiKayla MarshSareh KeshavarziWei XuHatem KremaAnthony M JoshuaMarcus O ButlerTrevor J PughPublished in: Cancer research communications (2023)
Here, we demonstrate integrated, longitudinal cfDNA sequencing using multi-omic approaches is more effective than unimodal analysis. This approach supports the use of frequent blood testing using comprehensive genomic, fragmentomic, and epigenomic techniques.