The Effect of Varying Interval Definitions on the Prevalence of SARS-CoV-2 Reinfections: A Retrospective Cross-Sectional Cohort Study.

Sjoerd M EuserTieme WeeninkJan M PrinsMilly HaverkortIrene MandersSteven van LelyveldBjorn L HerpersJan SinnigeJayant KalpoeDominic SnijdersJames Cohen StuartFred Slijkerman MegelinkErik KapteijnsJeroen den BoerAlex WagemakersDennis Souverein

Published in: Diagnostics (Basel, Switzerland) (2022)

Although the calculated reinfection prevalence was relatively low (0.11% for the 8-week time interval), choosing a different minimum interval between two positive tests resulted in major differences in reinfection rates. As reinfection Cp-values stabilized after 8 weeks, we hypothesize this interval to best reflect novel infection rather than persistent shedding.

Keyphrases

sars cov
cross sectional
risk factors
clinical trial
randomized controlled trial