Comparative effectiveness of sodium-glucose cotransporter-2 inhibitors and dipeptidyl peptidase-4 inhibitors in improvement of fatty liver index in patients with type 2 diabetes mellitus and metabolic dysfunction-associated steatotic liver disease: A retrospective nationwide claims database study in Japan.

Mitsuhiro Shikamura Atsushi Takayama Masato Takeuchi Koji Kawakami

Published in: Diabetes, obesity & metabolism (2024)

SGLT2is use appeared to be associated with a greater improvement of the FLI than DPP4i use in patients with T2DM and MASLD. In the absence of direct head-to-head comparisons from clinical studies, our study, using real-world data, may support physicians' decision-making in clinical practice.

Keyphrases

clinical practice
optic nerve
primary care
health insurance
oxidative stress
big data
cross sectional
fatty acid
skeletal muscle
adverse drug
drug induced