Safety and efficacy of very low LDL-cholesterol intensive lowering: a meta-analysis and meta-regression of randomized trials.

Giuseppe Patti Enrico Guido Spinoni Leonardo Grisafi Roxana Mehran Marco Giovanni Mennuni

Published in: European heart journal. Cardiovascular pharmacotherapy (2022)

This meta-analysis indicates that very low LDL-C levels on intensive lipid-lowering treatments are not associated with any adverse event and maintain a persistent reduction of cardiovascular events.

Keyphrases

cardiovascular events
systematic review
low density lipoprotein
coronary artery disease
cardiovascular disease
randomized controlled trial
emergency department
fatty acid
adverse drug