Low-Intensity Adjuvant Chemotherapy for Breast Cancer in Older Women: Results From the Prospective Multicenter HOPE Trial.
Mina S SedrakCan-Lan SunJingran JiHarvey J CohenCary P GrossWilliam P TewHeidi D KlepinTanya M WildesEfrat DotanRachel A FreedmanTracey O'ConnorSelina ChowMary Ann FentonBeverly MoyAndrew E ChapmanWilliam DaleVani KatheriaNicole M KudererGary H LymanAllison MagnusonHyman B MussPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2022)
One in five older patients with EBC treated with standard chemotherapy received low RDI and had inferior survival outcomes. Older patients at risk for low RDI should be identified and targeted upfront before initiating chemotherapy.