Modelling item scores of Unified Parkinson's Disease Rating Scale Part III for greater trial efficiency.

Yucheng ShengXuan ZhouShuying YangPeiming MaChao Chen

Published in: British journal of clinical pharmacology (2021)

This analysis generated clear evidence that longitudinal modelling of item scores can enhance trial efficiency and success. It also called for reassessing the placement of the tremor items in the instrument.

Keyphrases

phase iii
psychometric properties
study protocol
phase ii
clinical trial
deep brain stimulation
randomized controlled trial
parkinson disease
open label
cross sectional
patient reported outcomes
ultrasound guided