Multicenter phase II study of trifluridine/tipiracil for esophageal squamous carcinoma refractory/intolerant to 5-fluorouracil, platinum compounds, and taxanes: the ECTAS study.

Yukiko MoriOsamu KikuchiTakahiro HorimatsuHiroki HaraShuichi HironakaTakashi KojimaKen KatoTakahiro TsushimaRyu IshiharaKumi MukaiRyuji UozumiHarue TadaHiroi KasaiAtsushi KawaguchiManabu Muto

Published in: Esophagus : official journal of the Japan Esophageal Society (2022)

Trifluridine/tipiracil monotherapy is feasible and shows modest activity in patients with refractory esophageal squamous cell carcinoma.

Keyphrases

metastatic colorectal cancer
phase ii study
open label
locally advanced
high grade
clinical trial
squamous cell carcinoma
low grade
cross sectional
randomized controlled trial
radiation therapy
double blind
rectal cancer
placebo controlled