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Taking the brakes off telomerase.
Kamila Naxerova
Stephen J Elledge
Published in:
eLife (2015)
Studies using human embryonic stem cells have revealed how common cancer-associated mutations exert their effect on telomerase after cells differentiate into more specialized cell types.
Keyphrases
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embryonic stem cells
single cell
induced apoptosis
endothelial cells
cell cycle arrest
palliative care
cell therapy
pluripotent stem cells
oxidative stress
signaling pathway
stem cells
case control
cell proliferation