Taking the brakes off telomerase.

Published in: eLife (2015)

Studies using human embryonic stem cells have revealed how common cancer-associated mutations exert their effect on telomerase after cells differentiate into more specialized cell types.

Keyphrases

embryonic stem cells
single cell
induced apoptosis
endothelial cells
cell cycle arrest
palliative care
cell therapy
pluripotent stem cells
oxidative stress
signaling pathway
stem cells
case control
cell proliferation