Understanding the current acute aortic syndrome (AAS) pathways-The Collaborative Acute Aortic Syndrome Project (CAASP) protocol.
Jim ZhongGanesh VigneswaranNawaz Z SafdarIndrajeet MandalAminder A SinghSandip Nandhranull nullPublished in: PloS one (2024)
The study is a multicentre, retrospective service evaluation project of adult patients diagnosed on imaging with AAS. It will be coordinated by the UK National Interventional Radiology Trainee Research (UNITE) network and Vascular and Endovascular Research Network (VERN) in conjunction with The Aortic Dissection Charitable Trust (TADCT). All AAS cases diagnosed on imaging between 1st January 2018 to 1st June 2021 will be included and followed-up for 6 months. Eligibility criteria include aortic dissection (AD) Type A, Type B, non A/B, penetrating aortic ulcer, and intramural haematoma. Exclusion criteria are non-AAS pathology, acute on chronic AAS, and age<18. This project will evaluate patient demographics, timing of presentation, patient symptoms, risk factors for AD, physical examination findings, timing to imaging and treatment, hospital stay, and mortality. Univariate and multivariate analysis will be used to identify predictors associated with prolonged time to diagnosis or treatment and mortality at 30 days.
Keyphrases
- aortic dissection
- quality improvement
- case report
- high resolution
- mental health
- healthcare
- cross sectional
- cardiovascular events
- randomized controlled trial
- clinical trial
- type diabetes
- emergency department
- aortic valve
- fluorescence imaging
- liver failure
- hepatitis b virus
- study protocol
- coronary artery disease
- intensive care unit
- machine learning
- atrial fibrillation
- coronary artery
- deep learning
- pulmonary arterial hypertension
- acute respiratory distress syndrome
- acute care