Autoregulation in paediatric TBI-current evidence and implications for treatment.
Joseph E DonnellyAdam M H YoungKenneth M BradyPublished in: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery (2017)
Impaired autoregulation after traumatic brain injury is associated with a poor prognosis. Observational data suggests that optimal neurologic outcome and survival are associated with optimal perfusion pressure defined by autoregulation monitoring. No randomized, controlled, interventional data is available to assess autoregulation monitoring after pediatric traumatic brain injury.
Keyphrases
- poor prognosis
- traumatic brain injury
- long non coding rna
- cerebral blood flow
- electronic health record
- big data
- emergency department
- double blind
- intensive care unit
- open label
- severe traumatic brain injury
- magnetic resonance imaging
- cross sectional
- clinical trial
- combination therapy
- artificial intelligence
- young adults
- free survival
- magnetic resonance
- smoking cessation
- study protocol