Comparison of volumetric and 2D-based response methods in the PNOC-001 pediatric low-grade glioma clinical trial.

Marc von ReppertDivya RamakrishnanSarah C BrüningkFatima MemonSandra Abi FadelNazanin MalekiRyan BaharArman E AvestaLeon JekelMatthew SalaJan LostNiklas TillmannsManpreet KaurSanjay AnejaAnahita Fathi KazerooniAli NabavizadehMingDe LinKarl-Titus HoffmannKhaled BousabarahKristin R SwansonDaphne A Haas-KoganSabine MuellerMariam S Aboian

Published in: Neuro-oncology advances (2023)

Volumetric analysis of solid tumor was significantly better than 2D measurements in classifying tumor progression as determined by BT-RADS criteria and will enable more comprehensive clinical management.

Keyphrases

low grade
clinical trial
high grade
poor prognosis
phase ii
open label
study protocol
double blind
randomized controlled trial
phase iii
long non coding rna
clinical evaluation
placebo controlled