Exploring the long-term risk factors associated with intestinal failure-associated liver disease in pediatric and adult patients: The role of lipid injectable emulsions in the development of liver disease.

Marvick Melendez Daniel Dante Yeh

Published in: Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition (2022)

Serum PS correlates with liver biomarker abnormalities and is highest in SO-based ILE use compared with mixed-oil emulsions. Selection of a low-PS content ILE is recommended to reduce the risk of biliary cholestasis. Stimulation of the gut, if possible, is recommended to maintain gut integrity and reduce bacterial overgrowth. Fish oil (FO) shows promise in IFALD reversal however, large randomized controlled trials are needed to further establish support for the use of FO in adults.

Keyphrases

fatty acid
randomized controlled trial
big data
hyaluronic acid
drug induced
tissue engineering
meta analyses