Chitotriosidase: a biomarker of activity and severity in patients with sarcoidosis.

David BennettPaolo CameliNicola LanzaroneLoredana CarobeneNicola BianchiAnnalisa FuiLuigi RizziLaura BergantiniGiuseppe CillisMiriana d'AlessandroMaria Antonietta MazzeiRosa Metella RefiniPiersante SestiniElena BargagliPaola Rottoli

Published in: Respiratory research (2020)

Chitotriosidase is a reliable biomarker of sarcoidosis. It is increased in patients with sarcoidosis correlating with disease activity, severity and multiorgan dissemination. Steroid therapy tended to reduce chitotriosidase expression, however it responded in cases of disease relapse.

Keyphrases

disease activity
rheumatoid arthritis
systemic lupus erythematosus
rheumatoid arthritis patients
ankylosing spondylitis
poor prognosis
juvenile idiopathic arthritis
stem cells
free survival
bone marrow