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MicroRNA-374a, -4680, and -133b suppress cell proliferation through the regulation of genes associated with human cleft palate in cultured human palate cells.

Akiko SuzukiAimin LiMona GajeraNada AbdallahMusi ZhangZhongming ZhaoJunichi Iwata
Published in: BMC medical genomics (2019)
Our results indicate that miR-374a-5p, miR-4680-3p, and miR-133b regulate expression of genes that are involved in the etiology of human CP, providing insight into the association between CP-associated genes and potential targets of miRNAs in palate development.
Keyphrases
  • endothelial cells
  • cell proliferation
  • induced pluripotent stem cells
  • pluripotent stem cells
  • genome wide
  • poor prognosis
  • cell cycle
  • long non coding rna
  • genome wide identification