An analysis of silybin meglumine tablets in the treatment of drug-induced liver injury as assessed for causality with the updated Roussel Uclaf Causality Assessment Method using a nationwide database.

Bo ZhangGuosheng JiangLi WangXia LiChuan ZhaoQiliang TanWeiwei KangYuxia FengXian HanHafiz Khuram RazaYimin Mao

Published in: British journal of clinical pharmacology (2022)

Silybin meglumine tablets are safe and effective in DILI treatment. Large-scale and randomized controlled trials are required to further confirm their efficacy.

Keyphrases

randomized controlled trial
adverse drug
clinical trial
emergency department
drug induced
systematic review
cross sectional
double blind