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Anagliptin Monotherapy for Six Months in Patients With Type 2 Diabetes Mellitus and Hyper-Low-Density Lipoprotein Cholesterolemia Reduces Plasma Levels of Fasting Low-Density Lipoprotein Cholesterol and Lathosterol: A Single-Arm Intervention Trial.

Yuichi IkegamiYasuhiro TakenakaDaigo SaitoAkira ShimadaIkuo Inoue
Published in: Journal of clinical medicine research (2021)
Anagliptin monotherapy may have a beneficial effect on lipid metabolism, which could be mediated by the inhibition of hepatic cholesterol synthesis rather than the inhibition of intestinal lipid transport.
Keyphrases
  • low density lipoprotein
  • combination therapy
  • randomized controlled trial
  • open label
  • fatty acid
  • study protocol
  • clinical trial
  • insulin resistance
  • blood pressure
  • skeletal muscle
  • glycemic control