Long-Term High-Fat Diet Decreases Renal Insulin-Degrading Enzyme Expression and Function by Inhibiting the PPARγ Pathway.
Qian SuJuan HuangXi ChenYijie WangMuqing ShaoHongjia YanCaiyu ChenHongmei RenFuwei ZhangYinxing NiPedro A JoseJian ZhongJian YangPublished in: Molecular nutrition & food research (2023)
Long-term HFD decreases renal IDE expression and activity, and causes insulin resistance, which involves PPARγ.