Login / Signup

Whole-genome sequence and assembly of the Javan gibbon (Hylobates moloch).

Merly EscalonaJake VanCampenNicholas W MaurerMarina HauknessMariam OkhovatRobert S HarrisAllison WatwoodGabrielle A HartleyRachel J O'NeillPaul MedvedevKateryna D MakovaChristopher VollmersLucia CarboneRichard E Green
Published in: The Journal of heredity (2022)
The Javan gibbon, Hylobates moloch, is an endangered gibbon species restricted to the forest remnants of western and central Java, Indonesia, and one of the rarest of the Hylobatidae family. Hylobatids consist of four genera (Holoock, Hylobates, Symphalangus, and Nomascus) that are characterized by different numbers of chromosomes, ranging from 38 to 52. The underlying cause of this karyotype plasticity is not entirely understood, at least in part, due to the limited availability of genomic data. Here we present the first scaffold-level assembly for the Hylobates moloch using a combination of whole genome Illumina short-reads, 10X Chromium linked reads, PacBio, and Oxford Nanopore long reads and proximity ligation data. This Hylobates genome represents a valuable new resource for comparative genomics studies in primates.
Keyphrases
  • electronic health record
  • big data
  • climate change
  • south africa
  • single cell
  • single molecule
  • gene expression
  • machine learning
  • data analysis
  • genetic diversity