Amyloid-β-Induced Transglutaminase 2 Expression and Activities Are Modulated by 2-Pentadecyl-2-Oxazoline in Mouse and Human Microglial Cell Lines.

Transglutaminase 2 confirms its role as a neuroinflammation marker, the inhibition of which could be a potential preventive and therapeutic approach, while 2-pentadecyl-2-oxazoline is a potent modulator of the amyloid-β-induced Transglutaminase 2 expression and activities in mouse and human microglial cell lines.