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Expression and therapeutic targeting of Trop-2 in treatment resistant prostate cancer.

Jamie M SpergerKyle T HelzerCharlotte N StahlfeldDawei JiangAnupama SinghKatherine R KaufmannDavid J NilesErika HeningerNicholas R RydzewskiLiguo WangLiewei WangRendong YangYanan RenJohnathan W EnglePeng HuangChristos E KyriakopoulosSusan F SlovinHoward R SouleShuang G ZhaoManish KohliScott T TagawaWeibo CaiScott M DehmJoshua M Lang
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
These results support further studies on Trop-2 as a therapeutic and diagnostic target for mCRPC.
Keyphrases
  • prostate cancer
  • poor prognosis
  • radical prostatectomy
  • cancer therapy
  • binding protein
  • drug delivery