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Uncovering the expression patterns and the clinical significance of miR-182, miR-205, miR-27a and miR-369 in patients with urinary bladder cancer.

Nouha Setti BoubakerAymone GurtnerNesrine TrabelsiIsabella ManniHaroun AyedAhmed SaadiZeineb NaimiMeriem KsontiniMouna AyadiAhlem BlelSoumaya RammehMohamed ChebilGiulia PiaggioSlah Ouerhani
Published in: Molecular biology reports (2020)
Collectively, a selection of miRNAs was found to be aberrantly expressed in BCa suggesting a potential diagnostic value in BCa. In addition, the clinical value of miR-182 and miR-205 as potential prognosis biomarkers was highlighted. Indeed, our data provide additional insights into cancer biology. Further functional or target studies are mandatory to strengthen these findings.
Keyphrases
  • cell proliferation
  • long non coding rna
  • long noncoding rna
  • poor prognosis
  • squamous cell carcinoma
  • machine learning
  • risk assessment
  • big data
  • human health
  • binding protein
  • lymph node metastasis
  • squamous cell