Increased BMPR1A Expression Enhances the Adipogenic Differentiation of Mesenchymal Stem Cells in Patients with Ankylosing Spondylitis.

Zhenhua LiuPeng WangShuizhong CenLiangbin GaoZhongyu XieXiaohua WuHongjun SuYanfeng Wu Huiyong Shen

Published in: Stem cells international (2019)

Increased BMPR1A expression induces abnormal ASMSC adipogenic differentiation, potentially contributing to fat metaplasia and thus new bone formation in patients with AS.

Keyphrases

ankylosing spondylitis
poor prognosis
mesenchymal stem cells
pulmonary arterial hypertension
rheumatoid arthritis
binding protein
adipose tissue
fatty acid
pulmonary hypertension
systemic lupus erythematosus