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Dechlorane Plus increases adipogenesis in 3T3-L1 and human primary preadipocytes independent of peroxisome proliferator-activated receptor γ transcriptional activity.

Vian PeshdaryGabriella CalzadillaAnne LandryAlexander SoriskyElla Atlas
Published in: International journal of obesity (2005) (2018)
The current study shows that DP can induce adipogenesis of murine and human preadipocytes. We show that, although DP can directly activate PPARγ, its adipogenic effects may be mediated via other pathways.
Keyphrases
  • endothelial cells
  • induced pluripotent stem cells
  • pluripotent stem cells
  • gene expression
  • transcription factor
  • insulin resistance
  • metabolic syndrome
  • oxidative stress
  • fatty acid