Association of Neurofilament Light Chain, [ 18 F]PI-2620 Tau-PET, TSPO-PET, and Clinical Progression in Patients With β-Amyloid-Negative CBS.
Carla PalleisNicolai FranzmeierEndy WeidingerAlexander Maximilian BernhardtSabrina KatzdoblerStephan WallChristian FerschmannStefanie HarrisJulia SchmittSebastian SchusterJohannes GnörichAnika FinzeGloria BiecheleSimon LindnerNathalie L AlbertPeter BartensteinOsama SabriHenryk BarthelRainer RupprechtBrigitte NuscherAndrew W StephensBoris-Stephan RauchmannMatthias BrendelChristian HaassMatthias BrendelJohannes LevinGünter U HöglingerPublished in: Neurology (2023)
F]GE-180 TSPO-PET, and plasma-NfL show prognostic potential for clinical progression in patients with Aβ-negative CBS with probable 4-repeat tauopathy, which can be useful for clinical decision-making and stratifying patients in clinical trials.