The Opioid Analgesic Reduction Study (OARS) Pilot: A Double-Blind Randomized Multicenter Trial.
Cecile A FeldmanJ Fredericks-YoungerP J DesjardinsH MalmstromM MiloroG WarburtonB WardV ZiccardiD H FineP GreenbergT AndrewsP B MathesonS-E LuPublished in: JDR clinical and translational research (2023)
Study results suggest fixed-dose nonopioid combination ibuprofen 400 mg/acetaminophen 500 mg is superior to opioid-containing analgesic (hydrocodone 5 mg/acetaminophen 500 mg). This knowledge should inform surgeons and patients in the selection of postsurgical analgesia.
Keyphrases
- pain management
- end stage renal disease
- chronic pain
- clinical trial
- phase iii
- healthcare
- chronic kidney disease
- double blind
- study protocol
- ejection fraction
- phase ii
- randomized controlled trial
- newly diagnosed
- prognostic factors
- anti inflammatory
- liver injury
- cross sectional
- peritoneal dialysis
- patient reported
- drug induced
- thoracic surgery