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In vitro determination of the efficacy of illicit synthetic cannabinoids at CB1 receptors.

Shivani SachdevV Kiran VemuriSamuel D BanisterMitchell LongworthMichael KassiouMarina J SantiagoAlexandros MakriyannisMark Connor
Published in: British journal of pharmacology (2019)
All SCRAs tested showed substantially higher efficacy at CB1 receptors than ∆9 -THC, which may contribute to the adverse effects seen with these drugs but not ∆9 -THC.
Keyphrases
  • solid phase extraction
  • mass spectrometry
  • high resolution
  • liquid chromatography