A standardized nomenclature for resistance-modifying agents in the Comprehensive Antibiotic Resistance Database.

Keaton W SmithBrian P AlcockShawn FrenchMaya A FarhaAmogelang R RaphenyaEric D Brown Andrew G McArthur

Published in: Microbiology spectrum (2023)

While increasing rates of antimicrobial resistance undermine our current arsenal of antibiotics, resistance-modifying agents (RMAs) hold promise to extend the lifetime of these important molecules. We here provide a standardized nomenclature for RMAs within the Comprehensive Antibiotic Resistance Database in aid of RMA discovery, data curation, and genome mining.

Keyphrases

antimicrobial resistance
big data
adverse drug
small molecule
electronic health record
genome wide
emergency department
machine learning
dna methylation
artificial intelligence
data analysis