Eric D Brown

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 29

Top Venues

ACS infectious diseases

mBio

Nature chemical biology

Science advances

McMaster University

This page only lists publications with an associated author ORCID identifier.

Affiliation History

McMaster University

Canada

Professor :: Biochemistry and Biomedical Sciences

Publications

Franco K K Li, Liam J Worrall, Robert T Gale, Eric D Brown, Natalie C J Strynadka
Cryo-EM analysis of S. aureus TarL, a polymerase in wall teichoic acid biogenesis central to virulence and antibiotic resistance. Science advances 10 (9) (2024)
Franco K K Li, Liam J Worrall, Robert T Gale, Eric D Brown, Natalie C J Strynadka
Cryo-EM analysis of S. aureus TarL, a polymerase in wall teichoic acid biogenesis central to virulence and antibiotic resistance. Science advances 10 (9) (2024)
Caressa N Tsai, Marie-Ange Massicotte, Craig R MacNair, Jordyn N Perry, Eric D Brown, Brian K Coombes
Screening under infection-relevant conditions reveals chemical sensitivity in multidrug resistant invasive non-typhoidal Salmonella (iNTS). RSC chemical biology 4 (8) (2023)
Lindsey A Carfrae, Kenneth Rachwalski, Shawn French, Rodion Gordzevich, Laura Seidel, Caressa N Tsai, Megan M Tu, Craig R MacNair, Olga G Ovchinnikova, Bradley R Clarke, Chris Whitfield, Eric D Brown
Inhibiting fatty acid synthesis overcomes colistin resistance. Nature microbiology (2023)
Noor Abu Jarad, Kenneth Rachwalski, Fereshteh Bayat, Shadman Khan, Amid Shakeri, Roderick MacLachlan, Martin Villegas, Eric D Brown, Zeinab Hosseini-Doust, Tohid F Didar, Leyla Soleymani
A Bifunctional Spray Coating Reduces Contamination on Surfaces by Repelling and Killing Pathogens. ACS applied materials & interfaces (2023)
Keaton W Smith, Brian P Alcock, Shawn French, Maya A Farha, Amogelang R Raphenya, Eric D Brown, Andrew G McArthur
A standardized nomenclature for resistance-modifying agents in the Comprehensive Antibiotic Resistance Database. Microbiology spectrum (2023)
Luke N Yaeger, Shawn French, Eric D Brown, Jean Philippe Côté, Lori L Burrows
Central metabolism is a key player in E. coli biofilm stimulation by sub-MIC antibiotics. PLoS genetics 19 (11) (2023)
Kenneth Rachwalski, Michael J Ellis, Madeline Tong, Eric D Brown
Synthetic Genetic Interactions Reveal a Dense and Cryptic Regulatory Network of Small Noncoding RNAs in Escherichia coli. mBio 13 (4) (2022)
Brian P Alcock, William Huynh, Romeo Chalil, Keaton W Smith, Amogelang R Raphenya, Mateusz A Wlodarski, Arman Edalatmand, Aaron Petkau, Sohaib A Syed, Kara K Tsang, Sheridan J C Baker, Mugdha Dave, Madeline C McCarthy, Karyn M Mukiri, Jalees A Nasir, Bahar Golbon, Hamna Imtiaz, Xingjian Jiang, Komal Kaur, Megan Kwong, Zi Cheng Liang, Keyu C Niu, Prabakar Shan, Jasmine Y J Yang, Kristen L Gray, Gemma R Hoad, Baofeng Jia, Timsy Bhando, Lindsey A Carfrae, Maya A Farha, Shawn French, Rodion Gordzevich, Kenneth Rachwalski, Megan M Tu, Emily Bordeleau, Damion Dooley, Emma J Griffiths, Haley L Zubyk, Eric D Brown, Finlay Maguire, Robert G Beiko, William W L Hsiao, Fiona S L Brinkman, Gary Van Domselaar, Andrew G McArthur
CARD 2023: expanded curation, support for machine learning, and resistome prediction at the Comprehensive Antibiotic Resistance Database. Nucleic acids research (2022)
Craig R MacNair, Maya A Farha, Michael H Serrano-Wu, Katie K Lee, Brian Hubbard, Jean-Philippe Côté, Lindsey A Carfrae, Megan M Tu, Jeffrey L Gaulin, Diana K Hunt, Deborah T Hung, Eric D Brown
Preclinical Development of Pentamidine Analogs Identifies a Potent and Nontoxic Antibiotic Adjuvant. ACS infectious diseases 8 (4) (2022)
Jarrod W Johnson, Michael J Ellis, Zoë A Piquette, Craig R MacNair, Lindsey Carfrae, Timsy Bhando, Nikki E Ritchie, Paul Saliba, Eric D Brown, Jakob Magolan
Antibacterial Activity of Metergoline Analogues: Revisiting the Ergot Alkaloid Scaffold for Antibiotic Discovery. ACS medicinal chemistry letters 13 (2) (2022)
Tanisha Teelucksingh, Laura K Thompson, Shawna Zhu, Noah M Kuehfuss, James A Goetz, Stephanie E Gilbert, Craig R MacNair, Jennifer Geddes-McAlister, Eric D Brown, Georgina Cox
A genetic platform to investigate the functions of bacterial drug efflux pumps. Nature chemical biology 18 (12) (2022)
Kristina Klobucar, Emily Jardine, Maya A Farha, Marc R Mackinnon, Meghan Fragis, Brenda Nkonge, Timsy Bhando, Louis Borrillo, Caressa N Tsai, Jarrod W Johnson, Brian K Coombes, Jakob Magolan, Eric D Brown
Genetic and Chemical Screening Reveals Targets and Compounds to Potentiate Gram-Positive Antibiotics against Gram-Negative Bacteria. ACS infectious diseases 8 (10) (2022)
Sean D Workman, Jonathan Day, Maya A Farha, Sara S El Zahed, Chris Bon, Eric D Brown, Michael G Organ, Natalie C J Strynadka
Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria. Journal of medicinal chemistry 64 (18) (2021)
Maya A Farha, Shawn French, Eric D Brown
Systems-Level Chemical Biology to Accelerate Antibiotic Drug Discovery. Accounts of chemical research 54 (8) (2021)
Sara S El Zahed, Shawn French, Maya A Farha, Garima Kumar, Eric D Brown
Physicochemical and Structural Parameters Contributing to the Antibacterial Activity and Efflux Susceptibility of Small-Molecule Inhibitors of Escherichia coli. Antimicrobial agents and chemotherapy 65 (4) (2021)
Kristina Klobucar, Jean-Philippe Côté, Shawn French, Louis Borrillo, Amelia Bing Ya Guo, Michael H Serrano-Wu, Katie K Lee, Brian Hubbard, Jarrod W Johnson, Jeffrey L Gaulin, Jakob Magolan, Deborah T Hung, Eric D Brown
Chemical Screen for Vancomycin Antagonism Uncovers Probes of the Gram-Negative Outer Membrane. ACS chemical biology 16 (5) (2021)
Maya A Farha, Omar M El-Halfawy, Robert T Gale, Craig R MacNair, Lindsey A Carfrae, Xiong Zhang, Nicholas G Jentsch, Jakob Magolan, Eric D Brown
Uncovering the Hidden Antibiotic Potential of Cannabis. ACS infectious diseases 6 (3) (2020)
Shawn French, Amelia Bing Ya Guo, Eric D Brown
A comprehensive guide to dynamic analysis of microbial gene expression using the 3D-printed PFIbox and a fluorescent reporter library. Nature protocols 15 (2) (2020)
Madeline Tong, Shawn French, Sara S El Zahed, Wai Kit Ong, Peter D Karp, Eric D Brown
Erratum for Tong et al., "Gene Dispensability in Escherichia coli Grown in Thirty Different Carbon Environments". mBio 11 (6) (2020)
Kristina Klobucar, Shawn French, Jean-Philippe Côté, James R Howes, Eric D Brown
Genetic and Chemical-Genetic Interactions Map Biogenesis and Permeability Determinants of the Outer Membrane of Escherichia coli. mBio 11 (2) (2020)
Madeline Tong, Shawn French, Sara S El Zahed, Wai Kit Ong, Peter D Karp, Eric D Brown
Gene Dispensability in Escherichia coli Grown in Thirty Different Carbon Environments. mBio 11 (5) (2020)
Craig R MacNair, Eric D Brown
Outer Membrane Disruption Overcomes Intrinsic, Acquired, and Spontaneous Antibiotic Resistance. mBio 11 (5) (2020)
Maya A Farha, Craig R MacNair, Lindsey A Carfrae, Sara S El Zahed, Michael J Ellis, Hiu-Ki R Tran, Andrew G McArthur, Eric D Brown
Overcoming Acquired and Native Macrolide Resistance with Bicarbonate. ACS infectious diseases 6 (10) (2020)
Lindsey A Carfrae, Craig R MacNair, Christopher M Brown, Caressa N Tsai, Brent S Weber, Soumaya Zlitni, Vishwas N Rao, Joshua Chun, Murray S Junop, Brian K Coombes, Eric D Brown
Mimicking the human environment in mice reveals that inhibiting biotin biosynthesis is effective against antibiotic-resistant pathogens. Nature microbiology 5 (1) (2019)
Omar M El-Halfawy, Tomasz L Czarny, Ronald S Flannagan, Jonathan Day, José Carlos Bozelli, Robert C Kuiack, Ahmed Salim, Philip Eckert, Richard M Epand, Martin J McGavin, Michael G Organ, David E Heinrichs, Eric D Brown
Discovery of an antivirulence compound that reverses β-lactam resistance in MRSA. Nature chemical biology 16 (2) (2019)
Shawn French, Maya Farha, Michael J Ellis, Zaid Sameer, Jean-Philippe Côté, Nicole Cotroneo, Troy Lister, Aileen Rubio, Eric D Brown
Potentiation of Antibiotics against Gram-Negative Bacteria by Polymyxin B Analogue SPR741 from Unique Perturbation of the Outer Membrane. ACS infectious diseases 6 (6) (2019)
Sara M Imani, Roderick Maclachlan, Kenneth Rachwalski, Yuting Chan, Bryan Lee, Mark McInnes, Kathryn Grandfield, Eric D Brown, Tohid F Didar, Leyla Soleymani
Flexible Hierarchical Wraps Repel Drug-Resistant Gram-Negative and Positive Bacteria. ACS nano 14 (1) (2019)
Maya A Farha, Shawn French, Jonathan M Stokes, Eric D Brown
Bicarbonate Alters Bacterial Susceptibility to Antibiotics by Targeting the Proton Motive Force. ACS infectious diseases 4 (3) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Eric D Brown