Stratification by MYC expression has prognostic impact in MYC translocated B-cell lymphoma-Identifies a subgroup of patients with poor outcome.

Mette Ølgod PedersenAnne Ortved GangErik Clasen-LindeMarie Fredslund BreinholtHelle KnudsenSigne Ledou NielsenTim Svenstrup PoulsenTobias Wirenfeldt KlausenEstrid HøgdallPeter Nørgaard

Published in: European journal of haematology (2019)

These findings suggest that in patients with LBCL stratification by MYC protein expression level significantly improves the prognostic impact associated with MYC translocation.

Keyphrases

transcription factor
poor prognosis
diffuse large b cell lymphoma
randomized controlled trial
gene expression
binding protein
long non coding rna
study protocol
phase iii