Efficacy of Prednisolone for Bell Palsy in Children: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial.
Franz E BablDavid HerdMeredith Louise BorlandAmit KocharBen LawtonJason HortAdam WestShane GeorgeMichael ZhangKarthik VelusamyFrank M SullivanEd OakleyAndrew DavidsonSandy M HopperJohn Alexander CheekRobert BerkowitzStephen J C HearpsCatherine L WilsonAmanda WilliamsHannah ElboroughDonna LeggB PharmMark T MackayKatherine J LeeStuart R Dalzielnull nullPublished in: Neurology (2022)
Registered with the Australian New Zealand Clinical Trials Registry ACTRN12615000563561, registered 1 June 2015, ://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=368505&isReview=true CLASSIFICATION OF EVIDENCE: This study provides Class I evidence that for children with Bell's palsy, prednisolone does not significantly change recovery of complete facial function at one month. However, the study lacked the precision to exclude an important harm or benefit from prednisolone.