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The Blood And Clot Thrombectomy Registry And Collaboration (BACTRAC) protocol: novel method for evaluating human stroke.

Justin F FraserLisa A CollierAmy A GormanSarah R MarthaKathleen E SalmeronAmanda L TroutDanielle N EdwardsStephanie M DavisDouglas E LukinsAbdulnasser AlhajeriStephen GrupkeJill M RobertsGregory J BixKeith R Pennypacker
Published in: Journal of neurointerventional surgery (2018)
We have developed a novel tissue banking protocol using mechanical thrombectomy to capture thrombus along with arterial blood proximal and distal to it. The protocol provides high-quality specimens, facilitating analysis of the initial molecular response to ischemic stroke in the human condition for the first time. This approach will permit reverse translation to animal models for treatment development.
Keyphrases
  • endothelial cells
  • randomized controlled trial
  • atrial fibrillation
  • induced pluripotent stem cells
  • pluripotent stem cells
  • minimally invasive
  • acute ischemic stroke
  • brain injury
  • ultrasound guided