Early cardiac remodeling in aortic coarctation: insights from fetal and neonatal functional and structural assessment.
I SoveralF CrispiC WalterL GuiradoP García-CañadillaA CookA BonninH DejeaC Rovira-ZurriagaJ Sánchez de ToledoE GratacósJ M MartínezB BijnensO GómezPublished in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2020)
Our results suggest unique fetal cardiac remodeling in CoA, in which the LV stays smaller from the decreased growth stimulus of reduced volume load. Postnatally, the LV is acutely volume-loaded, resulting in an overall geometry change with higher filling velocities and preserved systolic function. These findings improve our understanding of the evolution of CoA from fetal to neonatal life. Copyright © 2020 ISUOG. Published by John Wiley & Sons Ltd.