Association Between Serum Lipids and Survival in Patients With Amyotrophic Lateral Sclerosis: A Meta-analysis and Population-Based Study.
Mark R Janse van MantgemWouter Van RheenenAnemone V HackengMichael A van EsJan Herman VeldinkLeonard H van den BergRuben P A van EijkPublished in: Neurology (2022)
Lipids may contain valuable information about disease severity and prognosis, but their main value may be driven as a consequence of disease progression. Our results underscore that gaining further insight into lipid metabolism and longitudinal data on serum concentrations of the lipid profile could improve the monitoring of patients and potentially further disentangle ALS pathogenesis.