Paeoniflorin Regulates NEDD4L/STAT3 Pathway to Induce Ferroptosis in Human Glioma Cells.
Xiao-Hu NieXiaochun JiYing XingJie XuBin LuShu-Fa ZhaoYun-Tao LiZhong-Zhou SuPublished in: Journal of oncology (2022)
In summary, this study demonstrated that paeoniflorin might function as an effective drug for glioma by inducing ferroptosis via upregulation of NEDD4L and repression of Nrl2, GPX4, and STAT3.