Early access to antiretroviral therapy versus standard of care among HIV-positive participants in Eswatini in the public health sector: the MaxART stepped-wedge randomized controlled trial.
Shaukat KhanDonna SpiegelmanFiona WalshSikhatele MazibukoMunyaradzi PasipamireBoyang ChaiRia ReisKhudzie MlamboWim DelvaGavin KhumaloMandisa ZwaneYvette FlemingEmma MafaraAnita HettemaCharlotte LejeuneAriel ChaoTill BärnighausenVelephi OkelloPublished in: Journal of the International AIDS Society (2021)
The observed improvement in retention in care and on the combined retention and viral suppression provides an important co-benefit of EAAA to HIV-positive adults themselves, at least in the short term. Our results from this "real world" health systems trial strongly support EAAA for Eswatini and countries with similar HIV epidemics and health systems. VL monitoring needs to be scaled up for appropriate care management.
Keyphrases
- hiv positive
- antiretroviral therapy
- men who have sex with men
- hiv infected
- human immunodeficiency virus
- south africa
- healthcare
- public health
- hiv infected patients
- randomized controlled trial
- hiv aids
- study protocol
- palliative care
- hiv testing
- quality improvement
- clinical trial
- pain management
- sars cov
- affordable care act
- phase iii
- systematic review
- phase ii
- global health