Short-chain fatty acids are key mediators of the favorable effects of the Mediterranean diet on intestinal barrier integrity: data from the randomized controlled LIBRE trial.
Benjamin SeethalerNguyen K NguyenMaryam BasraiMarion KiechleJens WalterNathalie M DelzenneStephan C BischoffPublished in: The American journal of clinical nutrition (2022)
Our data suggest that SCFAs are key mediators for the relation between diet and gut health. Assessment of SCFAs may form a basis for personalized nutrition in future clinical care. These results need to be verified in larger studies powered for this purpose, comprising different study populations. The trial was registered at clinicaltrials.gov as NCT02087592 and NCT02516540.
Keyphrases
- phase iii
- phase ii
- healthcare
- open label
- study protocol
- clinical trial
- electronic health record
- physical activity
- fatty acid
- double blind
- big data
- public health
- placebo controlled
- palliative care
- mental health
- randomized controlled trial
- current status
- quality improvement
- health information
- data analysis
- pain management
- machine learning
- climate change
- human health
- artificial intelligence
- clinical evaluation
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