Self-management intervention to reduce pulmonary exacerbations by supporting treatment adherence in adults with cystic fibrosis: a randomised controlled trial.
Martin J WildmanAlicia O'CathainChin MaguireMadelynne A ArdenMarlene HutchingsJudy BradleyStephen J WaltersPauline WhelanJohn AinsworthIain BuchanLaura MandefieldLaura SuttonPaul TappendenRachel A ElliottZhe Hui HooSarah J DrabbleDaniel Beevernull nullPublished in: Thorax (2021)
While pulmonary exacerbations and FEV1 did not show statistically significant differences, the intervention achieved higher objectively measured adherence versus usual care. The adherence difference might be inadequate to influence exacerbations, though higher BMI and lower perceived CF treatment burden were observed.
Keyphrases
- cystic fibrosis
- chronic obstructive pulmonary disease
- pseudomonas aeruginosa
- randomized controlled trial
- pulmonary hypertension
- physical activity
- mental health
- palliative care
- body mass index
- depressive symptoms
- social support
- risk factors
- quality improvement
- metabolic syndrome
- glycemic control
- air pollution
- weight loss