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Lactic acid-containing products for bacterial vaginosis and their impact on the vaginal microbiota: A systematic review.

Erica L PlummerCatriona S BradshawMichelle DoyleChristopher K FairleyGerald L MurrayDeborah BatesonLindi MassonJosephine SlifirskiGilda TachedjianLenka A Vodstrcil
Published in: PloS one (2021)
There is a lack of high-quality evidence to support the use of lactic acid-containing products for BV cure or vaginal microbiota modulation. However, adequately powered and rigorous randomised trials with accompanying vaginal microbiota data are needed to evaluate the efficacy of lactic acid as a BV treatment strategy.
Keyphrases
  • lactic acid
  • lipopolysaccharide induced
  • lps induced
  • clinical trial
  • open label
  • electronic health record
  • randomized controlled trial
  • study protocol
  • inflammatory response
  • combination therapy