Eye on genome editing.

Published in: The Journal of experimental medicine (2023)

CRISPR/Cas9 genome editing techniques have the potential to treat previously untreatable inherited genetic disorders of vision by correcting mutations that cause these afflictions. Using a prime editor, Qin et al. (2023. J. Exp. Med.https://doi.org/10.1084/jem.20220776) restored visual functions in a mouse model (rd10) of retinitis pigmentosa.

Keyphrases

genome editing
crispr cas
mouse model
genome wide
human health
copy number
gene expression
dna methylation
risk assessment