Characteristics of patients included and enrolled in studies on the prognostic value of serum biomarkers for prediction of postconcussion symptoms following a mild traumatic brain injury: a systematic review.
Eric MercierPier-Alexandre TardifMarcel EmondMarie-Christine OuelletÉlaine de GuiseBiswadev MitraPeter CameronNatalie Le SagePublished in: BMJ open (2017)
Most studies have recruited samples that are not representative and generalisable to the mTBI population. These exclusion criteria limit the potential use and translation of promising serum protein biomarkers to predict postconcussion symptoms.
Keyphrases
- mild traumatic brain injury
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- sleep quality
- case control
- cross sectional
- depressive symptoms
- physical activity
- patient reported outcomes
- climate change
- patient reported
- small molecule
- human health
- binding protein
- amino acid